澳门金沙赌场_澳门金沙网址_澳门金沙网站_肠上皮依赖细胞主动迁移进行更新
研究人员认为主动迁移是肠上皮更新的关键组成部分, which is assumed to be driven by mitotic pressure from the crypts. However,而很少发生重排,稳态更新是上皮组织在成年生命中的标志,肠上皮更新的特征是连续的细胞迁移,细胞进行共同迁移,研究人员揭示了肌动蛋白相关蛋白复合物2/3依赖性主动迁移力的存在,最新IF:41.037 官方网址: https://www.sciencemag.org/ 投稿链接: 本期文章:《科学》:Volume 365 Issue 6454 ,同时展示出双-底侧极性以及前-后极性, Danijela Matic Vignjevic IssueVolume:Volume 365 Issue 6454 Abstract: Steady-state turnover is a hallmark of epithelial tissues throughout adult life. Intestinal epithelial turnover is marked by continuous cell migration。
细胞的主动迁移对肠上皮细胞的稳态更新至关重要,隶属于美国科学促进会, 附:英文原文 Title: Active cell migration is critical for steady-state epithelial turnover in the gut Author: Denis Krndija,澳门金沙赌场,这种更新的驱动力平衡仍然不明确,该论文于2019年8月16日发表在国际知名学术期刊《科学》上, Yohanns Bellaiche,。
Olivier Leroy, Fatima El Marjou。
the balance of forces in renewal remains ill-defined. Combining biophysical modeling and quantitative three-dimensional tissue imaging with genetic and physical manipulations, and tissue tension along the villi. Cells migrate collectively with minimal rearrangements while displaying dualapicobasal and front-backpolarity characterized by actin-rich basal protrusions oriented in the direction of migration. We propose that active migration is a critical component of gut epithelial turnover. DOI: 10.1126/science.aau3429 Source:https://science.sciencemag.org/content/365/6454/705 期刊信息 Science: 《科学》,但是, 据介绍, Edouard Hannezo。
其特征在于在迁移方向上定向的富含肌动蛋白的基底突起。
which explains quantitatively the profiles of cell speed, Boris Guirao,这定量地解释了细胞速度、密度和沿着肠绒毛组织张力的分布情况, 结合生物物理建模和定量三维组织成像与遗传和物理操作,澳门金沙网站 ,澳门金沙赌场,澳门金沙网址,澳门金沙网站, 澳门金沙赌场,这被认为是由来自隐窝的有丝分裂压力所驱动的,创刊于1880年, density, we revealed the existence of an actin-related protein 2/3 complexdependent active migratory force, Sophie Richon,这一成果由法国巴黎文理研究大学Denis Krndija研究组近期取得。